smtp;541 5.4.1 Mail rejected by destination domain
The receiver refused the message for good and points at a network or routing problem (enhanced status 5.4.1). Use the wording above to pin down the exact fix.
Email provider · 4.x.x transient failure
Every SMTP 451 response on record from Zoho (zoho.com), with the verbatim text, the enhanced status code, a severity rating and a plain-English fix.
The receiver aborted the action because of a local error on its side, such as greylisting, a reputation or content check still running, or a short policy hold. Retries normally succeed once the hold clears.
smtp;541 5.4.1 Mail rejected by destination domain
The receiver refused the message for good and points at a network or routing problem (enhanced status 5.4.1). Use the wording above to pin down the exact fix.
Postmaster & documentation
The receiver aborted the action because of a local error on its side, such as greylisting, a reputation or content check still running, or a short policy hold. Retries normally succeed once the hold clears. At Zoho, it is a temporary deferral that is retried automatically, and the specific reason is in the enhanced status code and message text of each response below.
Match your bounce text to one of the responses below and follow its guidance. Recipient-side wording means fix the address. Authentication or reputation wording (SPF, DKIM, DMARC, blocklist) means fix your sending setup, and check Zoho's postmaster documentation.